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Description

The Danzer Laboratory is seeking a postdoctoral researcher to investigate basic mechanisms of temporal lobe epileptogenesis. The principal goal of this research is to determine the mechanisms by which altered mechanistic target of rapamycin (mTOR) signaling disrupt hippocampal circuit function and lead to the development of epilepsy. The research has the potential to lead to new therapies to treat epilepsy, which will be tested in preclinical studies. The fellowship will provide training opportunities in EEG/ECoG acquisition and analysis, confocal and two-photon live imaging, hippocampal circuitry, calcium imaging, optogenetics, DREADDs, transgenic models of epilepsy and grant writing/manuscript preparation.

MAJOR DUTIES AND RESPONSIBILITIES:

• Design, execute, and record laboratory experiments, and analyze the data.
• Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.
• Present research at laboratory meetings, journal clubs, seminars, and meetings.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Maintain currency in field through continuing education, literature, and seminars.
• Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.
• Perform other duties as assigned.

Cincinnati Children's Research and Training at a Glance:

• Among the top in NIH funding for pediatric research institutions
• Over 1.4 million square feet of research laboratory space
• 900+ scientists conducting basic, translational, and clinical research
• Over 2000 publications annually in top-tier journals
• Access to Employee Resource Groups and Mentorship programs
• Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.

Learn more about the Postdoctoral Fellowship Program.

Compensation and Benefits:

• Postdoctoral Research Fellows and Associates are eligible for:
  • Group Health, Dental, and Vision Insurance Plans
  • Paid Time Off
  • Retirement Plan
  • Tuition Reimbursement
  • Relocation Benefits for Eligible Hires

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Qualifications

EDUCATION\WORK EXPERIENCE: Ph.D. in related discipline, MD, or equivalent required.

The ideal candidate will have a doctoral degree in a relevant field along with experience in basic wet lab techniques and animal handling.

REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.

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